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Process R&D
Custom Research & Manufacturing
Contract Manufacturing
Chemistry Manufacturing & Control

Inogent has created capabilities to handle process development involving wide range of chemistry like Azides, Nitration, Chiral Synthesis, Cryogenic Rxns, Enzymatic Reactions, Decarboxylation, Cyanation, Bromination, Grignard, Chlorination, Diazotization, Acetylation , Reduction, Methylation, Oxidation etc.

The development capabilities are matched with capacities in Kilo Lab and Pilot Plant to scale up molecules to suit the supply requirements for various clinical phases from 1 Kg to 100 Kg levels.
Facilities:
One to Tens of Kg scale
l Glass Reactors, SS, Hastelloy & Glass lined reactors
l Capacities ranging from 20 - 250 L (5 - 66 US gal)
l Individual suites for reactors
l Wide range of reaction temperatures ((-70 to 200 deg C)
l Necessary support equipment for filtration, drying, milling, sieving etc.
Tens to Hundreds of Kg scale
l SS, Glass & Glass lined reactors
l Flexible lay out of reactors
l Wide range of reaction temperatures ((-70 to 200 deg C)
l Capacities ranging from 50 L - 2000 L
Total Capacity 8 KL
l Capacities ranging from 100 – 1000 L (26-2640 US gal)
l Operating Pressure up to 20 Bar
l Capability to handle cryogenic conditions at acidic pH
For effective combination of cost and capability advantage, new state of the art manufacturing facility is under construction. This is a cGMP compliant custom manufacturing block and will get commissioned in March 2010.
l 2 independent modules of Kilo Lab and 1 module of Pilot Plant
l Kilo Lab: Reactor capacity ranging from 50 L to 200 L.
l Pilot Plant: Reactor capacity ranging from 250 L to 3000 L.
l Dedicated powder processing areas – Class 100,000
l Necessary supporting equipment
l Utilities including Cryogenic (-85 C)
l Hot Oil (250 C) and Huber system (-85 to +200 deg C)
l Vacuum system (0.1 Torr) and Purified Water – USP 30
Chemistry and Scale Up Capabilities
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